The Story of Zeta Potential 2

Whenever we peer into the microscope to look at living blood, we inevitably come upon principles of chemistry and physics looking back at us. These principles are so core to existence itself that it seems odd that medicine has yet to incorporate these concepts in its practice and medical schools have yet to teach them to medical students. But having said that, it is also apparent that many who study in the naturopathic field as well have missed some of these ideas.

What makes this section so important is that if you get the gist of what is written here, you will discover keys to the secret of reversing and eliminating heart disease.

If you are imaging “live blood” for education with microscopy and have not taken a Biomedx training program, then it is quite possible you are about to learn in detail for the first time a most fundamental aspect of the blood which causes most of the pictures you see to be.

With that said, let’s get started with a little overview of some research that will lead into our main topic of discussion.

Insights From the Stealth Pathogen

Lida Mattman is a researcher who has written on the nature of these microorganisms in a book entitled “Cell Wall Deficient Forms – Stealth Pathogens”. This refers to the little microbial forms that show an ability to be present one moment and not the next, just like the microbial forms that come and go in the blood. They have this changeable stealth nature about them. In the introduction to her book she recounts the words of earlier researchers regarding this topic.

In 1892 Wilhelm Zopf wrote that it was thought that only micrococcus could produce micrococci, not rods or spirals, and similarly, spirals could give rise to spirals only and not to rods and cocci, and fungi are not able to pass through different stages. He stated that the old theory now only has historical significance.

In 1899 Willibald Winkler, MD, found remarkable deviations in forms, and using carefully prepared pure cultures, found that bacteria pass through stages with markedly different morphology. He stated his observations would likely not be accepted immediately.

100 years later these observations are still not generally accepted by medical thinkers.

A very insightful section of Lida Mattman’s book discusses how changing the terrain of the culture medium, changes the developmental form of the microbe. Examples: anthrobacter develop rods, rather than spheres if peptone is added to the glucose-mineral salts medium; whether triangle forms or ellipsoidal forms of yeast develop will be dependent on the amino acid mix in the medium; candida develops only budding yeast cells when glucose is the sole carbon source, but with soluble starch, glycogen, or dextrin, there is extensive filamentation; the presence of simple ions can determine the shape of an organism; for some fungi, mycelia form only when zinc, copper and iron cations are all present; excess zinc can prevent fungal sporulations.

All of this leads back to the terrain. The terrain is everything and it is the premise behind How You Rot & Rust.

In the human body, many think of the blood as a fluid, but it is more akin to a suspension, i.e. solid particles are suspended in a liquid.

In essence, blood is a suspension of colloids.

In colloid chemistry blood could easily be thought of as nothing more than a colloidal slurry and the principles that apply to any colloidal slurry or suspension also apply to the blood.  The term most apt to explain the coming together of the red blood cells and the various microbial forms in the blood is ZETA POTENTIAL. This relates to the electrical charge around a colloid. In the blood this is controlled by pH and all the other elements found in the “soup”.


All of life moves about with a constant interplay between the forces of ions. Ions are electrically charged atoms or groups of atoms. Anions are the negatively charged ions and are created through an electron gain and cations are the positively charged ions created through an electron loss. In colloidal chemistry the term used to discuss the charge around a colloidal particle is zeta potential.

When tiny minerals or organic particles (colloids) are suspended in a fluid, the negative ionic charge around the colloid is what maintains the dispersion or discreteness of the particles of the suspension.


In blood, the amount of the suspended particles, the pH of the suspension, the mix of anions and cations, all determine the rheological characteristics. Rheology is the word that describes the study of the deformation and flow of matter. Rheo is from Greek and it means flow.



It is interesting to note how for thousands of years Chinese medicine has always dealt with the concept of flow. If you don’t have flow then you must have congestion. If you have congestion then you don’t have flow. It’s the yin and yang of life. The up and down of balance. The in and out of health.


History Long Suppressed

Way back in 1628, Harvey presented his Thesis entitled “Motion of the Heart and Blood in Animals”. He stated: “The blood therefore required to have motion, and indeed such a motion that it should return to the heart; for sent to the external parts of the body, far from its fountain, as Aristotle says, and without motion, it would become congealed”. Another way of looking at it is the principle of flow. Harvey knew that disease induced coagulation of the blood. However he found peer pressure was so strong against his ideas that he feared for his life.

In 1878, Herman von Helmholtz established the mathematical basis for the physical chemistry covering the stability of liquid-solid systems, including milk, oil, emulsions, urine and blood. His mathematical theory forms the basic law of zeta potential today.

There were many other individuals that laid a foundation for the understanding of zeta potential and its practical application to health in the human body. However, if you ask any medical doctor like an oncologist or cardiovascular specialist – to whom these principles can be of critical importance – about zeta potential, they are apt to say they never heard that term before. This is likely because a study of zeta potential is not a part of the curriculum in medical school.

However, anyone who begins a serious study of biological terrain will encounter the concept of zeta potential because it is a basic principle of the electrical properties of life itself. And in one sense the body is electric—or electrostatic.


In various industries the concept of zeta potential is common knowledge. Zeta potential plays a critical role in many industrial processes. The manufacture of soap is one example. Water by itself does not always clean as well as it could. Sometimes the water needs to be made wetter. How can you have wetter water that becomes a better cleaner and disperser of dirt on grungy dishes? By adding anionic surfactants to the water thereby changing its charge. The anionic soapy water does a better job of getting between the cationic dirt particles of the dirty dishes and disperses the garbage.

The area of paints and pigments is another example. Whether a quantity of pigment added to a base paint will coagulate and form a speckled mess or disperse into trillions of tiny particles each remaining separate and discrete thereby leaving an even color, depends almost entirely on the electrical properties of the system.

In the industrial process of purifying water in treatment plants, zeta potential plays a crucial role.  In order to get out pollutants, the treatment facility pours in a highly cationic substances like aluminum sulfate which attracts the garbage to itself thereby coagulating or flocculating out the precipate. This floc becomes heavy and drops to the bottom of the holding tank thereby cleansing the water. (Note that if they miscalculate how much cationic aluminum to add to the water, some of that will stay in the water supply that arrives at your tap and this aluminized tap water is definitely not good for health as it coagulates elements of your own body fluids.)

In a general way of thinking which is overly simplistic, think of anions as dispersers, and cations as coagulators. Anions disperse things, cations bring things together. Further, you could say anionic leans alkaline, cationic leans acid.


Molecular Reality

Molecular compounds are composed of various atoms with electrons spinning in their orbits and is a mix of anionic and cationic components. The ratios of these anions to cations give indications as to the valence of the molecule or electrolyte. The ions of both anionic and cationic electrolytes may carry from one to four charges and are accordingly designated mono-, di-, tri-, or polyvalent type electrolytes.

When the electrolytes are negatively charged they are written as 1:1, 1:2, 1:3, 1:4 to indicate their ratios and their respective ionic strength. The higher the ratio the more ionic strength to increase zeta potential and have a dispersionary effect.  The right ionic balance is good for humans.

When the electrolytes are positively charged they are written as 1:1, 2:1, 3:1, 4:1. The higher these ratios, the more ionic strength to decrease zeta potential and coagulate, agglutinate, flocculate, sludge and downright clog up systems. The wrong ionic balance is bad for humans.

Negative Charge – 1:1, 1:2, 1:3, 1:4. Ratios indicate ionic strength.
Higher = more strength to increase zeta potential. Good for humans.

Positive Charge – 1:1, 2:1, 3:1, 4:1. Higher ratios here means more
strength to decrease zeta potential. Bad for humans.

A lot of the processed foods with chemical preservatives, pesticide residue and additives are of a cationic 1:1, 2:1 nature.  Bad for humans. These foods have a natural zeta potential lowering effect on the blood.  As it is, blood is naturally maintained in a dispersed state that is just on the verge of beginning to sludge. This is required for an effective blood clotting mechanism so if you cut yourself you don’t bleed to death. The blood clotting mechanism is associated with the release and activation of prothrombin-thrombin which is a cationic polyelectrolyte. (Heparin on the other hand is an anionic polyvalent electrolyte dispersing agent and is used medically to relieve intravascular coagulation – though I should say we can do this 100% naturally with an understanding of this information). Now with blood at a natural precipice just ready to sludge, if we add negative health items to our diet that have a further sludging effect on our blood, the situation for health begins to deteriorate.




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